A recent press release from the NIH, reported by Science Daily, announced a newfound effect of this drug: anti-depressant. Evidently one sub-anesthetic dose reduced the symptoms of depression in patients resistant to all other anti-depressant therapies. The effect was not trivial. From the NIH press release:
Depression improved within one day in 71 percent of all those who received ketamine, and 29 percent of these patients became nearly symptom-free within one day. Thirty-five percent of patients who received ketamine still showed benefits seven days later. Participants receiving a placebo infusion showed no improvement.That is something else! Due to its status as a controlled substance and the hallucinogenic side effects, it may be a while before this treatment gets approved. It is exciting none-the-less that there could be an entirely different approach to treating depression.